What helps / Not proven or did not work

CBD (cannabidiol)

CBD is a substance from the cannabis plant that does not make you high. Two small trials looked hopeful for social anxiety. Two bigger trials have finished, but their full results are not public.

Early evidence

Only two small trials have been published, with 24 and 37 people. A trial of 239 people finished in 2023 and a trial of 60 people in 2025, but neither has published full results. How we rate evidence

At a glance

Compared with other treatments
Better than a dummy pill in two small trials: one single dose before a speech test, and one 4-week trial in Japanese teenagers.
What it takes
Not approved for social anxiety. Shop CBD products vary a lot in dose and purity.

What it is

CBD (cannabidiol) is one of the substances in the cannabis plant. Unlike THC, it does not make you high. It is sold in many countries as oils, gummies and capsules. The rules differ a lot between countries.

CBD is not approved as a medicine for social anxiety anywhere we know of. In the US, the Food and Drug Administration has approved one CBD medicine, Epidiolex, and only for some rare forms of epilepsy. It warns that CBD products sold to treat diseases are unapproved drugs.

Why people try it

Many people want something natural, without the side effects of prescription drugs. Some people on Reddit say cannabis is the only time they feel like themselves around others. That is a real experience. But cannabis with THC and pure CBD are different things, and the trials tested CBD.

What the trials found

Small early trials often look better than later, larger ones. The same pattern happened with fasedienol and D-cycloserine. Until the two bigger trials report, we cannot say whether CBD helps.

What the bigger trials could tell us

The two unpublished trials are larger than the published ones. The EmpowerPharm trial gave 300 or 600 mg a day and measured social anxiety over 10 weeks. The NYU trial gave CBD for 3 weeks and measured anxiety during a speech test and in brain scans. If they found a clear benefit, CBD would move up. If they found little or nothing, that would be important too, because many people already buy CBD for anxiety. Either way, the results should be public. See trials waiting for results.

If you are thinking of trying CBD

Side effects

The FDA lists these risks of CBD: liver damage, harmful interactions with other drugs, and extreme sleepiness. The two small social anxiety trials were too short and too small to say much about safety.

What helps now

Cognitive therapy for social anxiety and SSRIs have many trials behind them. If you use alcohol or cannabis to get through social situations, alcohol and social anxiety explains why that can backfire. If you feel low or unsafe, see crisis lines.

Myths and facts

Myth:CBD is a proven treatment for social anxiety.

Fact:Only two small trials have been published. The largest trial finished in 2023, and its full results are still not public.

Myth:CBD and cannabis are the same thing for anxiety.

Fact:CBD does not make you high. Cannabis with THC is a different thing. The CBD trials tested CBD, not cannabis.

Sources

  1. Bergamaschi MM, Queiroz RH, Chagas MH, et al. (2011). Cannabidiol reduces the anxiety induced by simulated public speaking in treatment-naive social phobia patients.Neuropsychopharmacology.
  2. Masataka N (2019). Anxiolytic Effects of Repeated Cannabidiol Treatment in Teenagers With Social Anxiety Disorders.Frontiers in Psychology.
  3. EmpowerPharm Inc. (2023). Cannabidiol (CBD) for the Treatment of Social Anxiety Disorder (NCT05600114).ClinicalTrials.gov.
  4. EmpowerPharm (press release, trade coverage) (2024). EmpowerPharm announces Phase 2 trial results for CBD in social anxiety disorder.Clinical Trials Arena / PharmOutsourcing.
  5. NYU Langone Health (2025). Cannabidiol as a Treatment for Social Anxiety Disorder (R61) (NCT05571592).ClinicalTrials.gov.
  6. US Food and Drug Administration: regulation of cannabis and cannabis-derived products, including CBD
  7. US Food and Drug Administration: what you should know about using cannabis, including CBD