For therapists

Social anxiety disorder guidelines compared: NICE, Canada, BAP

All three guidelines put CBT and SSRIs at the centre. They disagree on whether therapy or medication comes first, on group CBT, and on benzodiazepines, pregabalin and beta-blockers.

The short answer

Checked against the source

All three main guidelines were read in full text for this page on 9 November 2026: NICE on nice.org.uk (earlier researchers had been blocked; it was accessible this time), the Canadian guideline in its open-access version on Europe PMC, and the BAP guideline from the BAP website. For the WFSBP guideline only the abstract was read, so its social-anxiety-specific line assignments are not shown here.

Side by side

QuestionNICE CG159Canada 2014BAP 2014
ScopeAdults, children and young people; psychological and drug treatmentAnxiety disorders, PTSD and OCD; medication and psychological treatmentMedication for anxiety disorders, PTSD and OCD, with notes on psychological treatment
First-line psychologicalIndividual CBT developed for SAD (Clark and Wells or Heimberg model)CBT, the “gold-standard” non-drug treatmentCBT; cognitive therapy appears superior to exposure
Group CBTDo not routinely offer it in preference to individual CBT: less clinically and cost effectiveGroup or individual; meta-analyses find no significant differenceNotes some evidence on cost-effectiveness of group CBT
Therapy or medication first?Therapy first; medication if CBT is declinedNot ranked against each other; several studies found similar acute efficacyBroadly similar acute efficacy; choose by features, preference and availability
Self-helpCBT-based supported self-help if individual CBT is declinedInternet CBT beat wait-list in RCTs; may widen accessNotes cost-effectiveness evidence for internet-delivered approaches
First-line medicinesSSRI: escitalopram or sertralineEscitalopram, fluvoxamine (and CR), paroxetine (and CR), pregabalin, sertraline, venlafaxine XRAn SSRI
Next stepsOther SSRI (fluvoxamine, paroxetine) or venlafaxine; then an MAOI (phenelzine or moclobemide)Second-line: alprazolam, bromazepam, citalopram, clonazepam, gabapentin, phenelzine. Third-line includes moclobemideRaise dose, switch, or combine evidence-based treatments; consider adding buspirone after partial SSRI response
BenzodiazepinesDo not routinely offerSecond-lineConsider in patients who have not responded to other approaches
Pregabalin, gabapentinDo not routinely offer anticonvulsantsPregabalin first-line; gabapentin second-lineListed among evidence-based acute options
Beta-blockersNot part of the recommended pathwayAtenolol and propranolol not recommended; footnote says beta-blockers are used in practice for performance situations such as public speakingAvoid atenolol in generalized SAD; small single-dose studies suggest benefit in performance anxiety
Psychodynamic therapyConsider if both CBT and medication are declined; less effective and less cost-effective than CBTNot statedNot stated
Mindfulness, supportive therapyDo not routinely offerNot statedNot stated
How long to continue medicationAt least a further 6 months after response in the first 3 months; taper when stoppingNot statedAt least 6 months after response
Combining drug and therapyAdd CBT for partial SSRI response after 10 to 12 weeks; add medication for partial CBT responseClonazepam added to paroxetine not recommendedNot routinely at the start; consider when initial treatments fail
Children and young peopleIndividual (8 to 12 × 45 min) or group (8 to 12 × 90 min) CBT; do not routinely offer medicationNot covered in the SAD section read hereNot stated
Things not to offerBotulinum toxin for sweating, endoscopic thoracic sympathectomy, St John’s wortBuspirone, imipramine, levetiracetam, quetiapine, beta-blockersAtenolol, buspirone (generalized SAD)

“Not stated” means the point was not found in the section of the guideline read for this page.

Where they disagree, and why

Benzodiazepines. NICE says no, routinely. Canada lists clonazepam, alprazolam and bromazepam second-line. BAP keeps them for people who have not responded. The trial base is thin: the later Cochrane review found a response risk ratio of 4.03, but from only 2 trials. Canada’s text gives lack of effect on common comorbidities as one reason for not making them first-line; dependence risk is the usual further reason for caution. Many people with social anxiety drink to cope, which adds a further reason for caution.

Pregabalin. Canada puts it first-line; NICE does not recommend anticonvulsants routinely. In a fixed-dose trial of 329 people, only 600 mg/day beat placebo. Misuse risk and the dose-dependence make the NICE position easier to defend. The Canadian ranking follows the existence of positive placebo-controlled trials.

Therapy first, or patient choice? NICE builds its pathway on its own network meta-analysis and economic model, which put individual cognitive therapy ahead on effect against placebo and on cost-effectiveness. BAP and Canada look mainly at acute efficacy, where drugs and therapy look similar. Both views are partly right. They use different outcomes (see why the rankings change).

Group CBT. NICE separates individual and group CBT because its analysis found a difference. Canada relied on older meta-analyses that did not.

Beta-blockers. All three agree they are not a treatment for generalized social anxiety disorder. For propranolol, a review found only one trial in social phobia, with 16 people; atenolol did not beat placebo in the trials Canada and BAP cite. Canada and BAP both acknowledge use for one-off performance situations.

How current are they?

What could not be checked

Sources

  1. National Institute for Health and Care Excellence (NICE) (2013). Social anxiety disorder: recognition, assessment and treatment (CG159).NICE clinical guideline.
  2. Katzman MA, Bleau P, Blier P, Chokka P, Kjernisted K, Van Ameringen M, et al. (2014). Canadian clinical practice guidelines for the management of anxiety, posttraumatic stress and obsessive-compulsive disorders.BMC Psychiatry.
  3. Baldwin DS, Anderson IM, Nutt DJ, et al. (2014). Evidence-based pharmacological treatment of anxiety disorders, post-traumatic stress disorder and obsessive-compulsive disorder: a revision of the 2005 guidelines from the British Association for Psychopharmacology.Journal of Psychopharmacology.
  4. Bandelow B, Allgulander C, Baldwin DS, et al. (2023). World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders - Version 3. Part I: Anxiety disorders.World Journal of Biological Psychiatry 24(2):79-117.
  5. Mayo-Wilson E, Dias S, Mavranezouli I, Kew K, Clark DM, Ades AE, Pilling S (2014). Psychological and pharmacological interventions for social anxiety disorder in adults: a systematic review and network meta-analysis.Lancet Psychiatry.
  6. Mavranezouli I, Mayo-Wilson E, Dias S, Kew K, Clark DM, Ades AE, Pilling S (2015). The Cost Effectiveness of Psychological and Pharmacological Interventions for Social Anxiety Disorder: A Model-Based Economic Analysis.PLoS One.
  7. Williams T, Hattingh CJ, Kariuki CM, Tromp SA, van Balkom AJ, Ipser JC, Stein DJ (2017). Pharmacotherapy for social anxiety disorder (SAnD).Cochrane Database of Systematic Reviews.
  8. Steenen SA, van Wijk AJ, van der Heijden GJ, van Westrhenen R, de Lange J, de Jongh A (2016). Propranolol for the treatment of anxiety disorders: Systematic review and meta-analysis.Journal of Psychopharmacology.
  9. Feltner DE, Liu-Dumaw M, Schweizer E, Bielski R (2011). Efficacy of pregabalin in generalized social anxiety disorder: results of a double-blind, placebo-controlled, fixed-dose study.International Clinical Psychopharmacology.
  10. NICE CG159: Social anxiety disorder: recognition, assessment and treatment (overview, published 22 May 2013, last reviewed 21 May 2024)
  11. NICE CG159: full recommendations
  12. Canadian clinical practice guidelines (Katzman et al. 2014), open-access full text on Europe PMC
  13. BAP guidelines for anxiety disorders (Baldwin et al. 2014), PDF from the British Association for Psychopharmacology